a drug administered orally for the treatment of erectile dysfunction. By inhibiting the action of the enzyme phosphodiesterase 5, it elevates local nitric oxide levels, causing smooth muscle relaxation and increased blood flow to the corpus cavernosum of the penis, which results in erection during sexual stimulation. Side-effects include headache, facial flushing, dyspepsia, nasal congestion, and dizziness. Because of severe adverse reactions, the drug is contraindicated in patients taking nitrate-based drugs, such as glyceryl trinitrate. Tadalafil (Cialis) and vardenafil (Levitra) are drugs with similar actions and effects.
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  • Sildénafil — Général Nom IUPAC …   Wikipédia en Français

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  • sildenafil — /sɪlˈdɛnəfɪl/ (say sil denuhfil) noun a drug, sildenafil citrate, which improves sexual function in males …  

  • sildenafil — A drug used to treat erectile dysfunction. Sildenafil relaxes the smooth muscle of the penis to allow increased blood flow and erection. It is a type of phosphodiesterase inhibitor. Also called Viagra …   English dictionary of cancer terms

  • sildenafil —  ou sildénafil  n.m. Médicament contre les troubles de l érection …   Le dictionnaire des mots absents des autres dictionnaires

  • sildenafil — noun virility drug (trade name Viagra) used to treat erectile dysfunction in men • Syn: ↑sildenafil citrate, ↑Viagra • Usage Domain: ↑trade name (for: ↑Viagra) • Hypernyms: ↑ …   Useful english dictionary

  • Sildenafil-Citrat — Dieser Artikel oder Abschnitt ist nicht hinreichend mit Belegen (Literatur, Webseiten oder Einzelnachweisen) versehen. Die fraglichen Angaben werden daher möglicherweise demnächst gelöscht. Hilf Wikipedia, indem du die Angaben recherchierst und… …   Deutsch Wikipedia

  • sildenafil citrate — noun The citrate salt of sildenafil, marketed as Viagra, a treatment for erectile dysfunction …   Wiktionary

  • sildenafil citrate — noun virility drug (trade name Viagra) used to treat erectile dysfunction in men • Syn: ↑sildenafil, ↑Viagra • Usage Domain: ↑trade name (for: ↑Viagra) • Hypernyms: ↑ …   Useful english dictionary

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